Fast, Ultrasensitive Detection of Reactive Oxygen Species Using a Carbon Nanotube Based-Electrocatalytic Intracellular Sensor

By Rawson, Frankie J.; Hicks, Jacqueline; Dodd, Nicholas; Abate, Wondwossen; Garrett, David J.; Yip, Nga; Fejer, Gyorgy; Downard, Alison J.; Baronian, Kim H. R.; Jackson, Simon K. & Mendes, Paula M.
Published in ACS Applied Materials \& Interfaces NULL 2015

Abstract

Herein, we report a highly sensitive electrocatalytic sensor-cell construct that can electrochemically communicate with the internal environment of immune cells (e.g., macrophages) via the selective monitoring of a particular reactive oxygen species (ROS), hydrogen peroxide. The sensor, which is based on vertically aligned single-walled carbon nanotubes functionalized with an osmi

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