QCM-I Mini 石英晶体微天平

with Impedance Measurement and Dissipation

The QCM-I MiniTM Quartz Crystal Microbalance is a high-sensitivity mass sensor which measures the change in frequency and dissipation of a quartz crystal resonator and any adsorbed film.  QCMs are useful in any number of applications - biosensors, chemical sensors, corrosion, polymer films, nanoparticle films, etc. Changes in frequency as well as dissipation give information relating to changes in mass or elasticity of films. 

The QCM-I, QCM-I Mini, and eQCM-I Mini are manufactured by MicroVacuum Ltd. (http://www.owls-sensors.com/) of Budapest, Hungary. MicroVacuum has integrated control of our USB-based potentiostats into their BioSense software (V3 or higher). Gamry has partnered with MicroVacuum for distribution of these instruments in the United States and China. Inquiries outside of the US and China can go directly to MicroVacuum (http://www.owls-sensors.com/contactus). 


QCM-I Mini Features:

  • Both frequency and quality of resonance (FWHM or Bandwidth or Dissipation) are measured
  • Different harmonics (up to the 13th Overtone at 5MHz Crystals) can be quickly and sequentially measured
  • Temperature control from 15° C to 60° (± 0,02° C) in included on one channel
  • Two independently measured channels
  • External PC with Windows® 10 Communication with QCM-I Mini via USB

software control measurement

 The software performs full control of the QCM-I Mini Instrument.  Two measurement modes are available:

  1. Resonance:  Measurement of resonance curve and calculation of the resonance frequency & FWHM up to 80 MHz
  2. QCM-t:  Continuous measurement of the resonance parameters and the temperature of the flow-cell.

Calculation:  Various QCM and ad-layer parameters can be calculated using standard or custom made models.  All these parameters can be displayed on the screen, printed, saved or can be exported for further evaluation.

What's Included:

  • QCM Unit with two channels (one channel is temperature controlled)
  • Microsoft® Surface Pro Tablet with Windows® 10 {ro
  • QSH-104 QCM Sensor Holder (flow through type)
  • BioSense 3.xx Software (one user license)

*Gamry is the exclusive distributor of MicroVacuum for the United States and China.  For information on other MicroVacuum Products or inquiries outside of the US & China, please visit their web site


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Technical Information

Measuring Principle

The QCM-I Mini unit is a high sensitivity mass sensor which measures
the change in frequency of a quartz crystal resonator and
as a label free biosensor it measures the “wet mass” of the
adsorbed layer in processes occurring at or near the sensor
surface. The measuring principle is based on impedance analysis
of the quartz crystal. The resonant frequency (fres) and the
bandwidth of the resonant conductance curve are determined.
The bandwidth or full width at half maximum (FWHM) is in direct
correlation with the quality factor (Q) which is by definition
the inverse of the well known dissipation (D).

Measurement Channels 2
1st : Temperature controlled
2nd : Connection for a variety of external sensor-holder modules
Frequency Range 1-80 MHz,up to the 13th overtone for a 5 MHz Crystal

Resonance Frequency
Sensitivity in Liquid

≤ 2 x 10-1 Hz

Dissipation Sensitivity
in Liquid

≤ 1 x 10-7

Mass Sensitivity in Liquid *

≤ 1 ng / cm- 1

Parameters Recorded
for each Overtone

Resonance Curve, Frequency, ΔFrequency, FWHM, ΔFWHM, Q,
Dissipation, ΔDissipation, Temperature, etc.

Temperature Control

Working Temperature 15 oC to 65 oC
Temperature Stability ± 0.02 oC
Temperature control Set manually or via software

Fluidic and Sample

Flow Cell Volume ~ 40 μl (typical with Ø14 mm crystals)
Wetted Parts  PTFE, PEEK, SS, VITON (or Kalrez )
Sample Loading Customer Supplied or Integrated Options
Pump  Customer Supplied, Syringe Pump or Integrated Peristaltic Options
Other Sample Cell Options

Electrochemical flow-cell, Open Cuvette, Immersion, Vacuum,
High-pressure, Remote Low-profile, Ellipsometry, Microscopy,

Physical Dimensions
(without the computer)

Dimensions, weight 180 mm x 175 mm x 68mm, 1.35 Kg


BioSense Universal software platform for QCM & EC measurements
Import / Export of data Export to third party software Excel, JPG, BPM, WMF etc. 
PC Control USB 2.0, Windows® 10 


Power Supply 12VDC power supply with universal input voltage
( 100V-240V AC / 50-60 Hz )

* The Sauerbrey relation is assumed to be valid.
All specifications are subject to change without notice.