Nitrogen-doped zinc oxide thin films biosensor for determination of uric acid
By Jindal, Kajal; Tomar, Monika & Gupta, Vinay
Published in Analyst
The Royal Society of Chemistry
2013
Abstract
Nitrogen-doped zinc oxide thin films (ZnO:N) have been realized as a potential matrix for the development of a uric acid biosensor. The correlation between the change in property of the ZnO film with N doping concentration and its biosensing response has been studied. The nitrogen dopant in a ZnO film alters its defects profile, thus improving the charge transfer characteristics and resulting in an enhanced peak oxidation current in the cyclic voltammogram in comparison to that of the pure ZnO film. The studies reveal that the bio-electrode based on the nitrogen-doped ZnO thin film matrix exhibits better sensitivity (1.1 mA mM-1 cm-2) with linearity over a wide range (0.05 mM to 1.0 mM) of uric acid concentration. A comparatively low value (0.10 mM) of the Michaelis-Menten constant (Km) indicates high affinity of the immobilized uricase towards uric acid. The proposed ZnO:N thin films matrix-based uric acid-biosensor has good reproducibility, a long shelf-life (20 weeks) and high selectivity.
Microsoft is Ending Support for Windows 7
Microsoft will discontinue support for Windows 7 on January 14, 2020 which means Gamry will also be discontinuing support for Windows 7. If you are upgrading to Windows 10, like many companies and institutions, you need to be running Version 7 of our s oftware . Please note that only USB and Ethernet-based instruments can run in Version 7. Eligible users can download the latest version of our software through our online Client Portal .
If you haven't already registered your instrument, you can do so through the Client Portal .
Please email Technical Support if you have any questions regarding this transition. Please be sure to include your instrument model and serial number when contacting us.