Ruthenium oxide based microelectrode arrays for in vitro and in vivo neural recording and stimulation
By Atmaramani, Rahul; Chakraborty, Bitan; Rihani, Rashed T.; Usoro, Joshua; Hammack, Audrey; Abbott, Justin; Nnoromele, Patrick; Black, Bryan J.; Pancrazio, Joseph J.; Cogan, Stuart F.
Published in Acta Biomaterialia
2019
Abstract
We have characterized the in vitro and in vivo extracellular neural recording and stimulation properties of ruthenium oxide (RuOx) based microelectrodes. Cytotoxicity and functional neurotoxicity assays were carried out to confirm the in vitro biocompatibility of RuOx. Material extract assays, in accordance to ISO protocol
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