In vitro and in vivo studies on the biodegradable behavior and bone response of Mg69Zn27Ca4 metal glass for treatment of bone defect

By Chen, Junxiu; Dong, Jiahui; Fu, Huameng; Zhang, Haifeng; Tan, Lili; Zhao, Dewei; Yang, Ke
Published in Journal of Materials Science & Technology 2019

Abstract

In the present work, the biodegradable behavior, cytocompatibility and osteogenesis activity of a Mg69Zn27Ca4 metal glass were investigated. Electrochemical test, immersion test, cytotoxicity test and histopathological evaluation were carried out. The results showed that there was a dense protective layer formed on the surface of Mg69Zn27Ca4 metal glass which could inhibit the degradation process in the Hank

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