A sintered graphene/titania material as a synthetic keratoprosthesis skirt for end-stage corneal disorders

By Li, Zhong; Goh, Tze-Wei; Yam, Gary Hin-Fai; Thompson, Brianna C.; Hu, Huanlong; Setiawan, Melina; Sun, Wen; Riau, Andri K.; Tan, Donald T.; Khor, Khiam Aik; Mehta, Jodhbir S.
Published in Acta Biomaterialia 2019

Abstract

An artificial cornea or keratoprosthesis requires high mechanical strength, good biocompatibility, and sufficient wear and corrosion resistance to withstand the hostile environment. We report a reduced graphene oxide-reinforced titania-based composite for this application. Graphene oxide nanoparticles (GO) and liquid crystalline graphene oxide (LCGO) were the graphene precursors and mixed with titanium dioxide (TiO2) powder. The composites reinforced with reduced GO or LCGO were produced through spark plasma sintering (SPS). The mechanical properties (Young

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